Table 3. Multivariable analysis of potential predictors of survival outcomes.
Factor | Overall survival |
Locoregional failure-free survival |
Distant metastasis-free survival |
|||||
---|---|---|---|---|---|---|---|---|
OR | P value | OR | P value | OR | P value | |||
Nomogram score: >125 vs. ≤125 | 0.57 | <0.001 | 0.48 | <0.001 | 0.57 | <0.001 | ||
Age at diagnosis | NS | NS | 0.98 | 0.025 | 0.96 | <0.001 | ||
Tumor histology: squamous vs. adeno | NS | NS | 1.59 | 0.025 | 0.51 | 0.005 | ||
Disease stage: III/IV vs. I/II | 2.28 | <0.001 | NS | NS | NS | NS | ||
Tumor length | NS | NS | 1.05 | 0.015 | NS | NS | ||
Nodal status: node+ vs. node- | NS | NS | NS | NS | 2.63 | <0.000 | ||
Total radiation dose, Gy | NS | NS | NS | NS | 0.95 | 0.048 | ||
Baseline PET scan: yes vs. no | 0.4 | 0.02 | NS | NS | NS | NS | ||
Baseline PET SUV (continuous) | NS | NS | NS | NS | 1.03 | 0.001 | ||
Primary tumor response on PET at 3 mo: < PR vs. CR | NS | NS | 1.63 | 0.029 | 1.98 | 0.011 |
OR, odds ratio; NS, not significant; PET, positron emission tomography; SUV, standardized uptake value; PR, partial response; CR, complete response.