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. 2014 Nov 14;32(1):69–75. doi: 10.1007/s10815-014-0372-3

Table 4.

Time lapse imaging results: Comparison of cell development duration between normal and abnormal embryos

Stage Normal embryos (n = 197) Mean duration (hours) (Mean ± SD) Abnormal embryos (n = 263) Mean duration (Mean ± SD) P value
tPB2 4.0 ± 2.2 4.5 ± 1.8 p > 0.05
tPNa 10.6 ± 3.4 10.8 ± 3.2 p > 0.05
tPNf 24.5 ± 4.3 25.8 ± 5.6 P < 0.05*
t2 28.3 ± 7.2 30.6 ± 9.7 P < 0.05*
t3 38.7 ± 7.0 39.7 ± 8.5 p > 0.05
t4 40.5 ± 7.2 41.5 ± 8.2 p > 0.05
t5 52.3 ± 8.6 50.1 ± 9.6 P < 0.05*
CC2 10.5 ± 4.2 9.1 ± 4.9 P < 0.05*
CC3 13.5 ± 5.6 10.8 ± 7.0 P < 0.05*
S2 1.8 ± 3.3 2.1 ± 4.0 p > 0.05
t5-t2 diff: 23.9 ± 7.4 20.1 ± 8.6 P < 0.05*

*Statistically significant

tPB2: Apperance of second polar body

tPNa: Appearance of pronuclei

tPNf : Both pronuclei faded

t2: Divison to 2 cells

t3: Divison to 3 cells

t4: Divison to 4 cells

t5: Divison to 5 cells

CC2: Duration of second cell cycle - from 2 to 3 cells

CC3: duration of the third cell cycle CC3 (t5-t3)

S2: Second synchrony

t5-t2 diff: Difference between t5 and t2