Table 2.
Summary of model findings The final simplified model based on stepwise regression analysis is reported in the third column
| . | Templeton (TM) | Templeton-Arvis (TMA) | Final Simplified ModeI | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| OR(3) | 95 %CI | Est(2) | OR(3) | 95 % | CI | Est(2) | OR(3) | 95%CI | Est(2) | ||
| Intercept(6)(age = 30) | 0.17 | 0.15, 0.20 | −1.77 | 0.23 | 0.07, | 0.72 | −1.48 | 0.29 | 0.17, | 0.49 | −1.24 |
| Age (1) | 1.01 | 1.01, 1.007 | 0.005 | 1.17 | 1.05, | 1.30 | 0.15 | 1.15 | 1.04, | 1.27 | 0.14 |
| Age2 (1) | 1.00 | 1.00, 1.000 | −0.0002 | 0.98 | 0.96, | 0.98 | −0.02 | 0.98 | 0.96, | 0.99 | −0.02 |
| Infertility duration: | 0.97 | 0.95, | 1.01 | −0.02 | |||||||
| 1 Year | 1.19 | .68,1.73 | 0.171 | ||||||||
| 4 years | 0.88 | 0.55, 1.39 | −0.012 | ||||||||
| 7 years | 0.78 | 0.54, 1.37 | −0.248 | ||||||||
| 13 years | 0.61 | 0.25, 0.99 | −0.494 | ||||||||
| Number of attempts | 0.87 | 0.71, 1.29 | −0.013 | 0.85 | 0.73, | 1.01 | −0.15 | ||||
| Tubal Infertility | 0.76 | 0.67, 1.39 | −0.271 | 0.40 | 0.13, | 1.19 | −0.90 | ||||
| ILB (8) | 2.01 | 1.65, 2.76 | 0.698 | 3.97 | 2.52, | 6.25 | 1.38 | 4.03 | 2.57, | 6.32 | 1.39 |
| INB(8) | 1.34 | 0.89, 2.55 | 0.292 | 0.76 | 0.39, | 1.45 | −0.27 | ||||
| NLB(8) | 1.21 | 0.77, 1.57 | 0.190 | 0.89 | 0.48, | 1.65 | −0.11 | ||||
| NNB(8) | 1.02 | 0.54, 1.41 | 0.019 | 0.84 | 0.43, | 1.65 | −0.17 | ||||
| Year (from 2011) | 1.23 | 1.07, | 1.40 | 0.21 | 1.22 | 1.07, | 1.39 | 0.20 | |||
| FSH >10 | 1.84 | 0.90, | 3.79 | 0.61 | |||||||
| BMI > 26 or <18 | 1.77 | 1.01, | 3.12 | 0.57 | |||||||
| AMH | 1.18 | 0.67, 1.85 | 0.16 | 2.28 | 1.376, | 3.768 | 0.731 | ||||
| C (Strict Model)(4) | 0.61 | 0.58, 0.66 | |||||||||
| C (Fitted model) (5) | 0.71 | 0.66, 0.75 | R2 = .067 (7) | 0.76 | 0.71, 0.80 | R2 = .14 (7) | 0.75 | 0.71, 0.80 | R2 = .14(7) | ||
1) Age and Age2 are polynomial components of age. (2) Est reports the parameter estimates of the logistic regression. (3) Odds Ratio (OR) and 95%CI calculated as exp(est), p values <0.001 are in bold underlined. (4) C = area under the ROC curve and 95%CI calculated on the strict model (no fitting). (5) C = area under the ROC curve and 95%CI calculated on the fitted model. (6) The intercept of the model depends on the selected reference in coding the predictors, and corresponds to age of 30 years. (7) Nagelkerke Determination (R2) coefficient of the Logistic model. (8) Female fertility history: ILB: previous IVF pregnancies resulting in LB, INB: previous IVF pregnancies not resulting in LB, NLB: previous Non-IVF pregnancies resulting in LB, NNB: previous Non-IVF pregnancies not resulting in LB