Table 2.
Change in cotinine glucuronidation per NEb | Change in nicotine glucuronidation per NEb | |||||||
---|---|---|---|---|---|---|---|---|
N | Betac | SEc | P-valued | N | Betac | SEc | P-valued | |
European Americans | 436 | −0.007 | 0.017 | 0.675 | 436 | −0.006 | 0.021 | 0.794 |
African Americans | 364 | 0.028 | 0.036 | 0.428 | 364 | −0.014 | 0.032 | 0.669 |
Latino Americans | 453 | −0.037 | 0.022 | 0.087 | 453 | −0.064 | 0.032 | 0.044 |
Japanese Americans | 674 | −0.011 | 0.012 | 0.385 | 674 | −0.047 | 0.014 | 1.30×10−3 |
Native Hawaiians | 311 | −0.038 | 0.024 | 0.125 | 311 | −0.100 | 0.031 | 1.40×10−3 |
Overall | 2239 | −0.012 | 0.009 | 0.164 | 2239 | −0.042 | 0.010 | 6.44×10−5 |
P-value for Heterogeneity | 1.26×10−25 | 7.69×10−11 |
Cotinine Glucuronidation is the ratio of the difference of total cotinine and free cotinine over total cotinine.
NE (Nicotine Equivalents) is the sum of total nicotine, total cotinine, and total 3'-hydroxycotinine expressed as nmol/mg creatinine.
Beta values and standard errors have been adjusted for age, gender (and race).
p-values adjusted for age, gender (and race).