Table 1. Characteristics of Study Population.
Premenopausal women | |||||
---|---|---|---|---|---|
Cases (n=945) |
Controls (n=1,418) |
||||
n | % 1 | n | % 1 | P 2 | |
Study | |||||
San Francisco Bay Area Breast Cancer Study | 430 | 46 | 666 | 47 | |
4-Corners Breast Cancer Study | 515 | 54 | 752 | 53 | |
Estrogen receptor (ER) and progesterone receptor (PR) status |
|||||
ER+PR+ | 575 | 61 | |||
ER+PR− | 86 | 9 | |||
ER−PR+ | 37 | 4 | |||
ER−PR− | 247 | 26 | |||
Age 3 (years) | |||||
<40 | 212 | 22 | 342 | 24 | |
40-49 | 564 | 60 | 837 | 59 | |
50-59 | 169 | 18 | 239 | 17 | |
Ethnicity/English language acculturation | |||||
Hispanic - low acculturation | 54 | 6 | 157 | 11 | <0.01 |
Hispanic - moderate acculturation | 196 | 21 | 339 | 24 | |
Hispanic - high acculturation | 247 | 26 | 269 | 19 | |
Non-Hispanic White | 448 | 47 | 653 | 46 | |
Percent Indigenous American admixture 4 | |||||
≤46 | 187 | 57 | 267 | 50 | 0.07 |
>46 | 140 | 43 | 267 | 50 | |
Education | |||||
Some high school or less | 148 | 16 | 313 | 22 | <0.01 |
High school graduate | 192 | 20 | 250 | 18 | |
Some college or higher | 605 | 64 | 855 | 60 | |
Family history of breast cancer in first-degree relatives |
|||||
No | 795 | 84 | 1278 | 90 | <0.01 |
Yes | 150 | 16 | 140 | 10 | |
Age at menarche (years) | |||||
<12 | 222 | 24 | 280 | 20 | <0.01 |
12-13 | 497 | 53 | 713 | 50 | |
≥14 | 226 | 24 | 425 | 30 | |
Full-term pregnancies | |||||
Nulliparous | 195 | 21 | 211 | 15 | <0.01 |
1-2 | 474 | 50 | 619 | 44 | |
3-4 | 227 | 24 | 469 | 33 | |
≥5 | 49 | 5 | 119 | 8 | |
Age at first full-term pregnancy (years) | |||||
Nulliparous | 195 | 21 | 211 | 15 | |
<25 | 376 | 40 | 669 | 47 | <0.01 |
25-29 | 207 | 22 | 321 | 23 | |
≥30 | 167 | 18 | 217 | 15 | |
Lifetime breastfeeding (months) | |||||
Nulliparous | 195 | 21 | 211 | 15 | <0.01 |
0 | 198 | 21 | 238 | 17 | |
1-12 | 294 | 31 | 463 | 33 | |
13-24 | 119 | 13 | 250 | 18 | |
≥25 | 139 | 15 | 256 | 18 | |
Oral contraceptive use | |||||
Current | 110 | 12 | 175 | 12 | 0.06 |
Former | 648 | 69 | 886 | 62 | |
Never | 187 | 20 | 357 | 25 | |
Alcohol consumption (g/day) 5 | |||||
0 | 473 | 50 | 783 | 55 | 0.09 |
0.1-9.9 | 314 | 33 | 435 | 31 | |
10.0-19.9 | 94 | 10 | 121 | 9 | |
≥20.0 | 64 | 7 | 79 | 6 |
Percentages may not add up to 100% due to rounding.
Mantel-Haenszel Chi-square test for difference between cases and controls.
Age at diagnosis (cases) or selection into the study (controls).
Among Hispanics only; based on the median in premenopausal controls.
In the reference year.