. Author manuscript; available in PMC: 2016 Jan 1.

Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2014 Oct 28;24(1):138–147. doi: 10.1158/1055-9965.EPI-13-1007-T

Table 4. Overall and Abdominal Body Size Associations with ER−PR− Breast Cancer in Premenopausal Women, by Ethnicity.

			All			Hispanics		Non-Hispanic Whites
	ER−PR− cases (n=247)	Controls (n=1,418)			ER−PR− cases (n=142)	Controls (n=765)		ER−PR− cases (n=105)	Controls (n=653)
	n	n	OR ¹ (95%CI)	OR ² (95%CI)	n	n	OR ² (95%CI)	n	n	OR ³ (95%CI)
Current height (m) ^4,5
T1: <1.56	70	468	1.0	1.0	59	394	1.0	11	74	1.0
T2: 1.56-1.63	75	466	1.07 0.75-1.55	1.10 0.76-1.60	45	252	1.13 0.73-1.75	30	214	0.89 0.42-1.88
T3: >1.63	102	482	1.50 1.03-2.19	1.52 1.03-2.24	38	117	2.01 1.24-3.25	64	365	1.01 0.50-2.03
			P_trend = 0.03	P_trend = 0.03			P_trend < 0.01			P_trend = 0.80
Young-adult BMI (kg/m²) ^4,6
T1: <20.6	88	446	1.0	1.0	46	157	1.0	42	289	1.0
T2: 20.6-23.1	84	446	0.90 0.64-1.26	0.82 0.58-1.17	51	230	0.77 0.48-1.24	33	216	0.87 0.51-1.47
T3: >23.1	59	459	0.63 0.43-0.93	0.44 0.28-0.69	38	339	0.36 0.20-0.63	21	120	0.67 0.32-1.37
			P_trend = 0.02	P_trend < 0.01			P_trend <0.01			P_trend = 0.27
Current BMI (kg/m²) ⁷
<25.0	106	576	1.0	1.0	53	212	1.0	53	364	1.0
25.0-29.9	76	446	0.99 0.71-1.38	0.80 0.55-1.15	48	286	0.68 0.42-1.10	28	160	1.01 0.57-1.78
≥30.0	65	394	0.98 0.69-1.40	0.59 0.35-0.99	41	265	0.49 0.25-0.96	24	129	0.85 0.38-1.87
			P_trend = 0.93	P_trend = 0.05			P_trend = 0.04			P_trend = 0.72
Current BMI (kg/m²) ^7,8, adjusted for young-adult BMI
<25.0			1.0	1.0			1.0			1.0
25.0-29.9			1.13 0.80-1.61	0.89 0.60-1.31			0.82 0.49-1.37			1.01 0.56-1.82
≥30.0			1.28 0.83-1.99	0.76 0.43-1.33			0.73 0.35-1.55			0.86 0.36-2.04
			P_trend = 0.26	P_trend = 0.34			P_trend = 0.41			P_trend = 0.77
Weight gain (kg) ^4,9
T1: <9.1	75	414	1.0	1.0	46	183	1.0	29	231	1.0
T2: 9.1-18.1	63	397	0.90 0.63-1.30	0.79 0.54-1.16	36	229	0.62 0.37-1.03	27	168	1.06 0.58-1.94
T3: >18.1	76	417	1.05 0.74-1.50	0.75 0.47-1.18	44	250	0.65 0.36-1.16	32	167	0.91 0.43-1.93
			P_trend = 0.79	P_trend = 0.20			P_trend = 0.14			P_trend = 0.83
Waist (cm) ⁴
T1: <81.3	72	463	1.0	1.0	31	158	1.0	41	305	1.0
T2: 81.4-93.6	79	458	1.16 0.81-1.66	1.33 0.91-1.93	52	289	1.36 0.81-2.29	27	169	1.17 0.67-2.03
T3: >93.6	86	459	1.29 0.91-1.84	1.86 1.16-3.01	54	301	2.17 1.13-4.17	32	158	1.45 0.70-2.98
			P_trend = 0.16	P_trend = 0.01			P_trend = 0.02			P_trend = 0.32
Hip (cm) ⁴
T1: <101.6	72	455	1.0	1.0	39	216	1.0	33	239	1.0
T2: 101.7-111.7	74	457	1.06 0.74-1.50	1.18 0.82-1.70	45	261	1.33 0.82-2.19	29	196	1.05 0.60-1.82
T3: >111.7	91	469	1.27 0.91-1.79	1.77 1.13-2.77	53	272	2.39 1.31-4.35	38	197	1.17 0.58-2.33
			P_trend = 0.16	P_trend = 0.02			P_trend = 0.01			P_trend = 0.68
Waist-to-hip ratio ⁴
T1: <0.79	67	455	1.0	1.0	28	135	1.0	39	320	1.0
T2: 0.79-0.85	87	455	1.35 0.95-1.93	1.41 0.98-2.02	49	271	1.09 0.64-1.84	38	184	1.68 1.02-2.77
T3: >0.85	83	470	1.34 0.92-1.95	1.46 0.98-2.19	60	342	1.26 0.73-2.17	23	128	1.57 0.85-2.89
			P_trend = 0.14	P_trend = 0.07			P_trend = 0.36			P_trend = 0.09
Waist-to-height ratio ⁴
T1: <0.51	69	455	1.0	1.0	27	123	1.0	42	332	1.0
T2: 0.52-0.59	79	455	1.22 0.85-1.75	1.43 0.98-2.11	50	291	1.17 0.68-2.03	29	164	1.43 0.82-2.48
T3: >0.59	89	470	1.40 0.97-2.03	2.19 1.33-3.60	60	334	2.11 1.07-4.15	29	136	1.99 0.94-4.23
			P_trend = 0.07	P_trend < 0.01			P_trend = 0.02			P_trend = 0.07

Odds ratios and 95% confidence intervals, adjusted for age (years, continuous), study (SFBCS, 4-CBCS), ethnicity/acculturation (low, moderate, high, non-Hispanic white), and average alcohol consumption in reference year (g/day; 0, 0.1-4.9, 5-9.9, 10-19.9, ≥

20).

Overall obesity measures additionally adjusted for waist circumference (continuous) and abdominal obesity measures additionally adjusted for current BMI (continuous).

Adjusted for all variables above except acculturation.

⁴

Based on tertiles among all premenopausal controls.

⁵

Based on measured height at interview (for SFBCS participants, self-reported adult height was used when measured height was not available).

⁶

Based on self-reported averaged weight at age 15 and age 30 for 4-CBCS cases and controls, self-reported weight in the 20’s for SFBCS cases and controls (between ages 25-30 for cases diagnosed from April 1995 to April 1998 and matched controls and between ages 20-29 for cases diagnosed from May 1998 to April 2002 and matched controls), and measured height at interview (for SFBCS participants, self-reported adult height was used when measured height was not available).

⁷

Based on self-reported weight in reference year (or measured weight at interview if self-reported weight in reference year was not available) and measured height at interview (or self-reported adult height for SFBCS participants for whom measured height was not available).

⁸

Adjusted additionally for young-adult BMI (continuous).

⁹

Based on self-reported weight in reference year (or measured weight at interview when self-reported weight was not available) minus self-reported young-adult weight; excludes 17 premenopausal ER−PR− cases and 125 premenopausal controls who lost weight.