. Author manuscript; available in PMC: 2016 Jan 1.

Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2014 Oct 2;24(1):94–104. doi: 10.1158/1055-9965.EPI-14-0804

Table 3C.

UGT variants nominally associated with the 3HC glucuronide ratio

UGT SNP/Variant	European American Smokers					African American Smokers
UGT SNP/Variant	Alleles		MAF	P^dom	Coef (95% CI)	Alleles		MAF	P^dom	Coef (95% CI)
UGT2B17 locus
copy number	1 : 0	↓	.303	.028	−0.15 (−0.29, −0.02)	1 : 0		.215

UGT2B7 locus
rs57216626	C : G		.448			C : G	↓	.250	.016	−0.14 (−0.25, −0.03)
rs4535394	C : T		.440			C : T	↓	.339	.026	−0.13 (−0.25, −0.02)

UGT2B17 0 allele: deletion allele. Alleles indicated as major : minor with impaired allele in bolded italics and an arrow indicating direction of effect for the minor allele. P^dom and coefficient with 95% confidence intervals from multivariate logistic regression modeling assuming a dominant effect of the minor allele and reported when P < .05. Variants ordered by location along chromosome 2 (UGT1A) and chromosome 4 (UGT2B). MAF: Minor allele frequency