Table 1. Patient characteristics at baseline MRI.
MCI/DLB (n = 10) |
MCI/AD (n = 27) |
MCI Stable (n = 20) |
P-value | |
---|---|---|---|---|
Female (%) | 1(10.0%) | 11(40.7%) | 7(35.0%) | 0.21 |
Age at scan, yr. | 68.3 (66.4, 82.9) | 79.9 (71.9, 84.2) | 79.5 (75.9, 83.3) | 0.16 |
Time interval, day | 494 (366,867) | 494 (438,953) | 654(475,962) | 0.19 |
Education, yr. | 14 (12, 19) | 13 (10, 17) | 14 (12, 16) | 0.33 |
Short Test of Mental Status | 31 (30, 33) | 30 (28, 32) | 31 (29, 34) | 0.25 |
CDR Sum of Boxes | 2 (0.88, 2.5) | 1 (0.5, 1.5) | 0.5 (0.5, 1.5) | 0.07 |
MMSE | 26 (23, 27) | 25 (24, 27) | 26 (24, 28) | 0.61 |
UPDRS | 8 (6, 11) | 0 (0, 3) | 0 (0, 5) | <0.001 |
Median (interquartile range) was reported for continuous variables. P-values for group-comparison are from Chi-square and Kruskal-Wallis Tests. MCI/DLB= Mild cognitive impairment (MCI) patients who progressed to dementia with Lewy bodies (DLB); MCI/AD =MCI patients who progressed to Alzheimer's disease (AD) dementia; MCI stable = MCI patients who remained MCI during follow up; MMSE: Mini Mental State Examination; CDR: Clinical Dementia Rating Sum of Boxes; UPDRS: Unified Parkinson's Disease Rating Scale;