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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: J Thromb Haemost. 2014 Nov 11;13(1):72–81. doi: 10.1111/jth.12755

Table 2.

Inhibitor titers of anti-human FVIII MAbs against ovine and porcine.

Inhibitor Domain Kinetics Group HumanTiter (BU/mg) Porcine Titer (BU/mg) Ovine Titer (BU/mg)
4A4 A2 I A 25,500 < 8 < 8
413 A2 I A 61,000 < 1 < 1
4F4 A2 I B 330 < 1 < 1
B25 A2 I C 18 < 4 < 1
1D4 A2 I E 51,000 5 6
G48 A2 II C * * *
2–54 A2 II D **** * *
3E6 C2 I A 11 < 1 < 4
I109 C2 I AB 3,100 < 1 < 1
D102 C2 I B 8,600 10 5
3D12 C2 I B 3,800 < 1 < 1
I14 C2 II BC **** * **
B75 C2 II BC * * *
3G6 C2 II BC **** * *
G99 C2 II BC **** * *
2–77 C2 II BC **** * *
I55 C2 II BC **** * *
ESH-8 C2 II C **** * *
2–117 C2 II C * * *
*

0–100 BU/mg;

**

100–1,000 BU/mg;

***

1,000–10,000 BU/mg;

****

> 10,000 BU/mg