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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Birth Defects Res B Dev Reprod Toxicol. 2014 Jun 30;101(4):300–307. doi: 10.1002/bdrb.21113

Figure 2.

Figure 2

PTU and MMI reduced serum T4 levels in rat dams treated during pregnancy. T4 serum levels were examined in pregnant rat dams at GD 20 following treatment from GD 6–19. All anti-thyroid drug treatments significantly reduced serum T4 levels. Dams were treated with vehicle (n = 9), 50 mg/kg PTU (n = 11), 100 mg/kg PTU (n = 8), 10 mg/kg MMI (n = 10), and 20 mg/kg MMI (n = 10). *p ≤ 0.0001.