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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Birth Defects Res B Dev Reprod Toxicol. 2014 Jun 30;101(4):300–307. doi: 10.1002/bdrb.21113

Figure 3.

Figure 3

PTU treatment induced lower body weights at GD 20 in rat dams. Dam weights were measured at GD 0, 6, 9, 12, 15, 18, and 20 in dams treated from GD 6–19 with vehicle, PTU, or MMI. A) Dam body weights were measured during pregnancy and at GD 20 they were significantly lower in PTU treated dams compared to vehicle controls. B) Changes in dam body weight from GD 6 to GD 20 revealed that PTU treated dams gained less weight over the treatment period. C) Examining the adjusted body weights (total dam weight-gravid uterus weight) showed no difference in weight among all treatment groups. Pregnant rats were treated with vehicle (n = 9), 50 mg/kg PTU (n = 11), 100 mg/kg PTU (n = 8), 10 mg/kg MMI (n = 10), and 20 mg/kg MMI (n = 10). *p ≤ 0.0001.