Figure 1.

A proposed model of the relationship between apoptosis cell death in epilepsy models. AIF (apoptosis-inducing factor); Apaf 1 (apoptosis protease activating factor-1); Bcl-2 (antiapoptotic protein); Bax (proapoptotic proteins); CAD (caspase activated DNase); ICAD (inhibitor of caspase activated DNase); NOS (nitric oxide synthase), ON (oxide nitric); OONHO⁻ (peroxide nitrite); LPO (lipid peroxidation); ROS (reactive oxygen species); RNS (reactive nitrogen species); Ca²⁺ (calcium); FADD (Fas-associated protein with death domain); Cyto c (cytochrome c).