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Mechanism for induction of cerebral vasospasm by interleukin-1 (GPCR = G-protein coupled receptor, PKC = protein kinase C, MLCK = myosin light chain kinase, MLC = myosin light chain, MBS = myosin-binding subunit of myosin light chain phosphatase, MLCPh = myosin light chain phosphatase, -P indicates phosphorylated state, PLC = phospholipase C, and IP3 = phosphatidylinositol trisphosphate).
