The reduction in long-time diffusion coefficient as a function of radius in simulation of sphere and molecular-shaped system with steric repulsion. Open spheres and filled spheres are for the values in sphere system and molecular-shaped systems, respectively. Three values of the reduction in diffusion of GPF measured in vivo of DH5α (1, 2), BL21(DE3) (1, 2s), and K-12 (1, 2) E. coli are also shown for comparison. The values corresponding to GFP diffusivity are surrounded by the dashed line to guide the eye.