Table 1.
Demographic and clinical characteristics of patients based on PainDETECT score
| PainDETECT ≤12 n = 25 | PainDETECT 13-18 n = 9 | PainDETECT ≥19 n = 16 | P value | |
|---|---|---|---|---|
| Demographic and clinical | ||||
| Age, years | 66 ± 9 | 63 ± 9 | 67 ± 7 | 0.392* |
| Female, n (%) | 18 (72%) | 5 (56%) | 10 (63%) | 0.629‡ |
| Weight, kg | 82.5 ± 14.1 | 81.0 ± 10.6 | 87.0 ± 18.9 | 0.587* |
| OA duration, years | 7.7 ± 8.1 | 7.4 ± 6.6 | 8.1 ± 4.6 | 0.528* |
| BMI, kg/m2 | 31 ± 6 | 29.9 ± 3 | 33 ± 6 | 0.558* |
| NSAID users, n (%) | 3 (12%) | 0 (0%) | 5 (31%) | 0.114¶ |
| PainDETECT | 8.1 ± 2.6 | 15.6 ± 1.1 | 24.2 ± 4.2 | <0.001♦ |
| WOMAC | ||||
| Pain (0–100) | 43 ± 17 | 50 ± 13 | 65 ± 14 | <0.001♦ |
| Function (0–100) | 45 ± 23 | 52 ± 15 | 68 ± 14 | <0.001♦ |
| Stiffness (0–100) | 51 ± 24 | 49 ± 18 | 69 ± 16 | 0.007♦ |
| Total (0–100) | 45 ± 21 | 51 ± 14 | 68 ± 13 | <0.001♦ |
| VAS pain (0–100 mm) | 62 ± 14 | 62 ± 13 | 69 ± 13 | 0.023♦ |
| Kellgren-Lawrence score | 0.068†§ | |||
| 2 | 14 (56%) | 5 (56%) | 5 (31%) | |
| 3 | 11 (44%) | 4 (44%) | 11 (69%) | |
| Inflammatory biomarkers | ||||
| Sedimentation rate, mm | 12.4 ± 9.0 | 12.6 ± 5.5 | 15.2 ± 20.8 | 0.406♦ |
| CRP, mg/l | 4.3 ± 2.9 | 6.8 ± 9.1 | 5.0 ± 4.7 | 0.432♦ |
Results are shown as mean ± standard deviation (SD) unless otherwise indicated. P values were assessed using the *Kruskal-Wallis test, the ‡chi-square test, the ¶Fisher’s exact test, the ♦Jonckheere-Terpstra test for trend, or the †Cochran-Armitage trend test; §Includes both Kellgren-Lawrence scores. n, number of participants; OA, osteoarthritis; BMI, body mass index; NSAID, non-steroidal anti-inflammatory drug; WOMAC, Western Ontario and McMaster Universities Osteoarthritis Index (each subscale, 100 = worst score; total scale, 100 = worst score); VAS, visual analog scale (0 mm = no pain, 100 mm = most severe pain); CRP, C-reactive protein.