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. 2014 Dec 12;14:479. doi: 10.1186/1472-6882-14-479

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© Shareef et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Bar diagrams showing the dose-dependent antidiarrhoeal effect of the crude extract of O. turpethum black variety (OTB) (A), and its hexane fraction (OTB.Hex) (B) and ethyl acetate fraction (OTB.EtOAc) (C) in castor oil-induced diarrhoea in mice. The symbols represent mean ± S.E.M, n = 5. One-way ANOVA followed by Tukey’s post-test. *P < 0.05; **P < 0.01 and ***P < 0.001 show a comparison of saline group to caster oil group and caster oil group to drug treated groups.