Table 1.
Demographic and clinicopathological characteristics.
| Characteristics | n = 64 (%) |
|---|---|
| Gender | |
| Male | 42 (65.6%) |
| Female | 22 (34.4%) |
| Age (yr) | |
| Range | 18–77 |
| Median | 47 |
| Stage at presentationa | |
| cT3N0 | 39 (60.9%) |
| cT4N0 | 2 (3.1%) |
| cT3N+x | 23 (35.9%) |
| Distance from anal verge (AV)b | |
| AV-2 cms | 25 (39.1%) |
| 2–5 cms | 15 (23.4%) |
| 5–10 cms | 20 (31.3%) |
| >10 cms | 04 (6.3%) |
| Pretreatment CEA (ng/mL)c | |
| Range | 1.1–127 |
| Median | 3.2 |
| Surgery | |
| Abdominoperineal resection (APR)d | 29 (45.3%) |
| Low anterior resection | 10 (15.6%) |
| Anterior resection | 22 (34.3%) |
| Intersphincteric resection | 03 (4.6%) |
| Histology | |
| Classical adenocarcinoma | 50 (78.1%) |
| Mucinous adenocarcinoma | 5 (7.8%) |
| Signet cell adenocarcinoma | 9 (14.06%) |
| Extracellular mucin pool | |
| Yes | 24 (37.5%) |
| No | 40 (62.5%) |
| Total nodes dissected | |
| Range | 1–21 |
| Median | 08 |
| Radiotherapy type | |
| Long course | 67 (95.7%) |
| Short course | 03 (4.3%) |
| Radiotherapy dose | |
| 50 GY | 48 (75%) |
| 40–45 GY | 14 (22%) |
| 25 GY | 02 (3.1%) |
| Laparoscopy | |
| Yes | 11 (17.2%) |
| No | 53 (82.8%) |
| Interval of NACTRT to surgery (days) | |
| Range | 12–206 |
| Median | 56.5 |
| Postoperative chemotherapy | |
| Yes | 39 (60.9%) |
| No | 25 (39.1%) |
aClinicoradiological staging.
bAV: anal verge.
cCEA: carcinoembryonic antigen.
dAPR indicates abdominoperineal resection.
xN+: positive nodal status.