Table 2.
Paracrine factors in media.
| Normoxia | Hypoxia | |||
|---|---|---|---|---|
| 5% | 20% | 5% | 20% | |
| VEGF (n = 6) | 1447.7 ± 93.5a | 2102.37 ± 138.7 | 1601.17 ± 66.3a | 2247.37 ± 83.6 |
| MCP-1 (n = 6) | 3964.4 ± 244.9a | 4985.1 ± 160.1 | 1880.0 ± 141.3ab | 2705.7 ± 143.8b |
| MIP-1α (n = 6) | 5.8 ± 0.4 | 6.2 ± 0.2 | 5.3 ± 0.5 | 6.0 ± 0.4 |
| MIP-1β (n = 5) | 5.1 ± 0.6 | 4.1 ± 0.1 | 4.0 ± 0.1ab | 3.5 ± 0.2b |
| MMP-2 (n = 6) | 37.3 ± 1.0a | 26.8 ± 2.2 | 28.6 ± 1.3ab | 19.7 ± 0.2b |
Data reported as mean ± SE in pg/mL except for MMP-2 (ng/mL). 5% and 20% refer to the amount of serum supplement present in the media. a P < 0.05 versus 20%; b P < 0.05 versus normoxia.