Table 2.
Analytical performance and analyte determination in pharmaceuticals by the proposed method (n = 5).
| Figures of merit | Vitamin A | Vitamin C | Rose Bengal |
|---|---|---|---|
| Calibration equation [I= intensity, c = concentration (μg/mL)] | I = 67.88c + 2.62 | I = 70.15c + 2.91 | I = 47.98c + 1.71 |
| Linear range (μg/mL) | 0.05–15 | 0.01–20 | 0.1–50 |
| Limit of detection (μg/mL, S/N = 3) | 0.008 | 0.005 | 0.05 |
| Sample throughput | 70 | 70 | 30 |
|
| |||
| Pharmaceutical formulations | Proposed method results/ (labeled values) (μg) |
Proposed method results/ (labeled values) (mg) |
Proposed method results/ (labeled values) (%) |
|
| |||
| Capsules | 210 ± 3/(200) | — | — |
| Chewable dragee | 9975 ± 5/(9900) | 97 ± 6/(100) | — |
| Eye drops (0.6 mL) | — | — | 1 ± 0.1/(1) |
| Injections | 3378 ± 4/(3300) | — | — |
| Tablets | — | 509 ± 5 mg/(500) | — |