Table 2.
Control | HF | Post FO | Post SP | Post SF | Pre-SF | HF + SF | |
---|---|---|---|---|---|---|---|
Body weight, g | |||||||
Week 0 | 110.2 ± 3.3a | 112.6 ± 8.5a | 112.0 ± 12.3a | 111.7 ± 9.5a | 112.2 ± 9.3a | 112.6 ± 7.8a | 110.5 ± 11.1a |
Week 4 | 120.1 ± 11.0b | 113.9 ± 10.0ab | 112.3 ± 11.6ab | 114.2 ± 11.7ab | 113.5 ± 12.6ab | 129.7 ± 10.0c | 110.1 ± 8.6a |
Week 8 | 134.3 ± 14.6b | 117.4 ± 10.5ab | 119.0 ± 12.6ab | 125.2 ± 8.9b | 118.1 ± 12.0ab | 132.5 ± 10.1b | 110.9 ± 8.8a |
Change in body weight, g | 14.2 ± 5.7c | 3.5 ± 8.5ab | 6.7 ± 4.2b | 10.9 ± 7.2bc | 4.7 ± 6.9ab | 2.9 ± 6.7ab | 0.8 ± 2.8a |
Food intake, g/day | 7.6 ± 0.1d | 7.5 ± 0.3d | 6.9 ± 0.1b | 7.5 ± 0.1d | 6.6 ± 0.3b | 7.2 ± 0.2c | 5.8 ± 0.6a |
Food efficiency, % | 7.6 ± 3.3c | 0.5 ± 1.3ab | 3.6 ± 2.3bc | 5.4 ± 3.6c | 2.6 ± 3.9b | 1.5 ± 3.4ab | 0.5 ± 1.9a |
Liver wet weight, g | 4.3 ± 0.7a | 7.3 ± 0.8c | 6.1 ± 0.7b | 6.0 ± 0.9b | 6.2 ± 0.8b | 7.1 ± 0.8c | 6.8 ± 0.6c |
Relative liver weight, % | 3.2 ± 0.3a | 6.4 ± 0.7d | 5.1 ± 0.3bc | 4.8 ± 0.5b | 5.3 ± 0.5c | 5.4 ± 0.3c | 6.1 ± 0.5d |
Aorta wet weight, mg | 33.0 ± 1.4ab | 34.3 ± 2.1b | 32.4 ± 4.3a | 32.6 ± 1.6ab | 33.5 ± 1.5a | 32.4 ± 1.3a | 34.1 ± 1.4b |
Relative aorta weight, % | 0.02 ± 0.001a | 0.03 ± 0.003bc | 0.03 ± 0.003b | 0.03 ± 0.003ab | 0.03 ± 0.003b | 0.02 ± 0.002a | 0.03 ± 0.003c |
Data are presented as mean ± SD (n = 12/group). Values in a row not sharing the same superscript letter are significantly different at p < 0.05. HF: high fat diet + cholesterol; post FO: fish oil diet after induction with HF diet; post SP: spirulina diet after induction with HF diet; Post SF: spirulina and fish oil diet after induction with HF diet; Pre-SF: pre-treatment with spirulina and fish oil diet before induction with HF diet; HF + SF: HF diet combined with spirulina and fish oil.