Table 3.

Distant intra-cerebral control (univariate analysis)

	At 6 months	At 12 months	P-value
Treatment approach
Radiosurgery alone (n = 98)	68	48
Radiosurgery + WBI (n = 50)	96	83	< 0.001
Radiosurgery dose
<20 Gy (n = 63)	72	63
≥20 Gy (n = 85)	82	59	0.92
Age
≤59 years (n = 76)	79	61
≥60 years (n = 72)	75	61	0.88
Gender
Female (n = 68)	80	57
Male (n = 80)	75	64	0.52
ECOG Performance Score
0-1 (n = 93)	77	61
2 (n = 55)	79	61	0.84
Histology
Adenocarcinoma (n = 92)	76	56
Others (n = 56)	81	71	0.17
Number of cerebral metastases
1 (n = 90)	81	72
2-3 (n = 58)	73	44	0.002
Maximum diameter of all cerebral metastases
≤18 mm (n = 75)	82	63
≥19 mm (n = 73)	72	59	0.16
Main site of cerebral metastases
Supratentorial (n = 127)	77	59
Infratentorial (n = 21)	82	72	0.39
Extra-cerebral metastases
No (n = 95)	81	63
Yes (n = 53)	73	57	0.36
Interval from lung cancer diagnosis to irradiation
≤11 months (n = 77)	83	58
≥12 months (n = 71)	73	62	0.75

Significant p-values are given in bold.