Table 2.

Multivariate Cox regression analysis of 5-year overall and disease-free survival of 86 HCC patients

Variables	Overall survival			Disease-free survival
	HR	95% CI	P	HR	95% CI	P
No. of tumor nodules	1.701	0.666-4.342	0.267	1.064	0.209-5.421	0.940
Venous infiltration	1.054	0.999-1.112	0.056	1.067	0.504-2.260	0.865
Edmondson-Steiner grading	2.230	0.937-5.308	0.070	1.971	0.827-4.696	0.126
TNM tumor stage	1.023	1.002-1.044	0.032*	1.055	1.019-1.092	0.003*
Fibulin-5 expression in tumor	2.148	1.255-3.677	0.005*	3.547	1.644-7.653	0.001*

TNM, tumor-node-metastasis; HR, hazard ratio; CI, confidence interval. *Statistically significant.