Figure 6.
Selective inhibition of STAT3 by Celecoxib, T2 and T3. A. Celecoxib, T2 and T3 inhibited STAT3 phosphorylation (Y705). Compounds T2 and T3 were more potent than Celecoxib at inhibiting P-STAT3. B. Celecoxib showed inhibition of STAT3 phosphorylation induced by IL-6 but not STAT1 phosphorylation by Interferon-γ.