Table 3.
List of differentially expressed proteins and their relevant GO annotations.
| PROTEIN | CTRL | FHS | SIGNIFICANCE FROM GO ANNOTATION |
|---|---|---|---|
| Protocadherin 15 | + | − | Adult walking behavior and calcium ion binding |
| Similar to myosin-9 | + | − | Blood vessel development |
| Vascular endothelial growth factor C (VEGF) isoform-2 | + | − | Growth factor activity |
| Aczonin | + | − | Calcium ion binding |
| Mitogen-activated protein kinase kinase kinase 1 | + | − | Ubiquitin mediated proteolysis |
| Cullin 2 | − | + | Ubiquitin mediated proteolysis |
| Thyroid hormone receptor interactor 12 | − | + | Ubiquitin mediated proteolysis |
| Zinc finger homeodomain 4 | + | − | Regulation of transcription |
| SET domain containing 1B | + | − | Regulation of transcription |
| Prohibitin 2 | − | + | Regulation of transcription |
| Zinc finger homeobox 3 | − | + | Regulation of transcription |
| Telomeric repeat binding factor (NIMA-interacting) 1 | − | + | Regulation of transcription |