TABLE 2.
Percentage (%) change from baseline in acne lesion counts (Week 12)
| LESION TYPE (MEAN % ± SD) | TREATMENT ARM | % CHANGE ADOLESCENT FEMALE GROUP (12-17 YRS OF AGE | % CHANGE ADULT FEMALE GROUP (≥18 YRS OF AGE) | p VALUEa |
|---|---|---|---|---|
| Inflammatory lesions | Dapsone Vehicle | -56.2 ± 33.3 -48.0 ± 40.6 |
-60.0 ± 33.3 -56.8 ± 34.7 |
0.3 |
| Noninflammatory lesions | Dapsone Vehicle | -35.5 ± 41.8 -23.5 ± 48.8 |
-47.4 ± 38.6 -42.3 ± 35.6 |
<0.0001 |
| Total lesions | Dapsone Vehicle | -44.0 ± 32.7 -33.7 ± 35.8 |
-52.8 ± 29.7 -48.3 ± 30.3 |
0.0008 |
a
Comparison between age groups
Adolescent females: dapsone treated, n=347; vehicle treated, n=317
Adult women: dapsone treated, n=434; vehicle treated, n=489