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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Future Med Chem. 2014 Oct;6(15):1645–1658. doi: 10.4155/fmc.14.98

Figure 2. Solution structure of ShK toxin (PDB id 1ROO).

Figure 2

ShK is oriented such that the pore-inserting lysine (K22) points downward. Three disulfide bridges between C3-C35, C12–C28 and C17–C32 are indicated, as well as the following interactions: D5–K30, K18–R24 and T6–F27. NMR structure of ShK toxin was determined in [66].