Table 1.
Demographic data and laboratory results of the three arms at baseline
| Arm A (n = 49) | Arm B (n = 31) | Arm C (n = 20) | Statistics | P value | |
| Median age (yr) | 45 (38-52) | 40 (36-50) | 43.5 (40.5-55) | F = 0.8400 | 0.4345 |
| Male:Female | 41:8 | 25:6 | 15:5 | χ2 = 0.6979 | 0.7050 |
| HBeAg-positive, n (%) | 13 (26.53) | 21 (67.74)a | 14 (70)a | χ2 = 17.7676 | 0.0000 |
| Median PLT (× 109/L) | 109 (73-150) | 109 (89-144) | 98.25 (76.5-122) | χ2 = 2.4880 | 0.2882 |
| Median PT (s) | 13.40 (12.6-14.3) | 12.75 (12-13.7)c | 14.30 (13-15.5) | χ2 = 10.1270 | 0.0063 |
| Median albumin (g/L) | 44 (39-46.8) | 43 (40-47.6) | 43.5 (40.9-47.3) | F = 0.0400 | 0.9600 |
| Median TB (μmol/L) | 17.35 (14.5-23.35) | 15.8 (13.1-20.1) | 18.35 (15.9-23.6) | χ2 = 2.1780 | 0.3366 |
| Median ALT (U/L) | 55 (43.2-87.5) | 51 (34.5-82) | 64 (48.5-91.6) | F = 0.400 | 0.6730 |
| Median AST (U/L) | 55 (41.05-68.5) | 49 (30-57) | 54.15 (45.5-66.5) | F = 1.5100 | 0.2251 |
| Median HBV DNA (log10 IU/mL) | 5.86 (5.16, 6.58)c | 6.06 (5.77, 6.39)c | 6.7 (6.29, 7.17) | F = 5.0300 | 0.0084 |
a
P <0.05 vs Arm A;
c
P <0.05 vs Arm C. HBeAg: Hepatitis B e antigen; PLT: Platelet counts; PT: Prothrombin time; TB: Total bilirubin; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; HBV: Hepatitis B virus.