Study enrollment flow diagram. aIncludes 6 samples rejected for culture because >3 days had elapsed since collection, 4 samples that were not tested for reasons that were not documented, 2 specimens that arrived when the Xpert machine was not operating because it was undergoing routine maintenance, and 1 specimen that was not one of the first 2 samples collected. bThree patients provided specimens for the study on 2 separate admissions, with each episode analyzed independently. Abbreviations: AFB, acid-fast bacilli; Xpert, Gene Xpert MTB/RIF assay.