Table 3.

Prediction of subsequent all-cause dementia and AD by depressive symptoms, activity variables, and social support entered pairwise into covariate-unadjusted and -adjusted models

	Model 1 (not adjusted for covariates)				Model 2 (adjusted for age, sex, education, ApoE4, MMSE, and IADL)
	all-cause dementia		AD		all-cause dementia		AD
	HR	95% CI	HR	95% CI	HR	95% CI	HR	95% CI
Depressive symptoms and activities (combined prediction)
GDS-15	1.06*	1.01 – 1.12	1.06	0.99 – 1.12	1.05	0.99 – 1.10	1.03	0.97 – 1.10
Global activities	0.21***	0.15 – 0.31	0.19***	0.12 – 0.30	0.37***	0.25 – 0.57	0.33***	0.20 – 0.54
Depressive symptoms and social support (combined prediction)
GDS-15	1.16***	1.10 – 1.22	1.15***	1.08 – 1.22	1.11***	1.05 – 1.17	1.09*	1.02 – 1.17
K-14	1.59	0.73 – 3.47	1.35	0.54 – 3.39	1.82	0.76 – 4.36	1.50	0.54 – 4.20

^*p < 0.05

^***p < 0.001.