Table 2.
Association between maternal body mass index (BMI) in early pregnancy (continuously measured) and asthma phenotypes in the offspring among mothers with BMI ≥ 18.5 (N = 2343)
| Asthma phenotypes | n (%) | OR | 95% CI | OR | 95% CI |
|---|---|---|---|---|---|
| Early transient | 137 (5.9) | 1.02 | 0.77–1.36 | 0.92 | 0.66–1.29 |
| Persistent | 149 (6.4) | 1.31 | 1.03–1.67 | 1.29 | 0.98–1.70 |
| School-age onset | 213 (9.1) | 1.22 | 0.98–1.52 | 1.15 | 0.88–1.50 |
Information on outcome at all ages was required for the disease-free groups resulting in lower numbers of included children compared with the GEE analyses.
Odds ratio (OR) and 95% confidence intervals (CI) are obtained from logistic regression analyses and represent 5 kg/m2 increase in maternal BMI. Adjusted for gender, maternal age, parental history of allergic disease, older siblings, socio-economic status and maternal smoking in pregnancy and/or at baseline.
Additionally adjusted for overweight in the offspring at 16 years.