Table IV.
Variables influencing ICU survival (n = 164 patients)
| Effects on ICU survival (univariate analysis) | OR (95% CI) | P value | N | |
|---|---|---|---|---|
| Reason for admission | ||||
| Sepsis | 0·708 (0·367–1·367) | 0·304 | 27/93 (29%) | |
| Respiratory | 0·543 (0·281–1·053) | 0·071 | 24/91 (26%) | |
| Renal | 0·422 (0·135–1·315) | 0·137 | 4/22 (18%) | |
| Haemodynamic | 0·451 (0·144–1·415) | 0·172 | 4/21 (19%) | |
| Neurological | 0·692 (0·070–6·818) | 0·753 | 1/4 (25%) | |
| Donor | ||||
| UD versus Sib | 0·946 (0·491–1·820) | 0·867 | 26/79 (33%) vs. 27/58 (32%) | |
| Conditioning | ||||
| RI versus MA | 2·887 (1·357–6·142) | 0·006 | 19/37 (51%) vs. 34/127 (27%) | |
| Organ support | ||||
| NIV | 0·390 (0·178–0·856) | 0·019 | 13/50 (21%) | |
| MV | 0·093 (0·042–0·208) | <0·001 | 11/83 (12%) | |
| Inotropes | 0·176 (0·083–0·373) | <0·001 | 13/87 (15%) | |
| Renal | 0·243 (0·100–0·590) | 0·002 | 7/52 (13%) | |
| No ventilatory support versus NIV only versus MV ± NIV | 0·240 (0·147–0·389) | <0·001 | 23/33 (70%) vs. 7/37 (37%) vs. 11/94 (12%) | |
| Number of organs supported | ||||
| 0 vs. 1 vs. 2 vs. 3 | 0·385 (0·273–0·541) | <0·001 | 33/33/45/45 | |
| Neutrophil count | 1·013 (0·931–1·102) | 0·768 | ||
| Platelet count | 1·006 (1·000–1·011) | 0·062 | ||
| Urea | 0·930 (0·885–0·977) | 0·004 | ||
| Bilirubin | 1·000 (0·996–1·003) | 0·978 | ||
| APACHE II | 0·930 (0·883–0·980) | 0·006 | ||
| Duration of ICU stay | 0·952 (0·907–0·998) | 0·042 | ||
| Duration of MV | 0·982 | 0·694 | ||
| Combined duration of NIV ± MV | 0·945 | 0·170 | ||
| Year of ICU admission | 1·102 | 0·072 | ||
| Number of ICU admissions | 0·976 (0·611–1·559) | 0·920 | ||
| Effects on ICU survival (multivariate analysis) | OR (95% CI) | P value |
|---|---|---|
| MV | 0·071 | <0·001 |
| Urea | 0·931 | 0·007 |
| Conditioning intensity | 3·27 | 0·023 |
ICU, intensive care unit; OR, odds ratio; 95% CI, 95% confidence interval; UD, unrelated donor; Sib, matched sibling donor; RI, reduced intensity; MA, myeloablative; NIV, non-invasive ventilation; MV, mechanical ventilation; APACHEII, Acute Physiology and Chronic Health Evaluation Score.