TABLE. Phenotypic and genotypic characteristics of macrolide resistant isolates.
| Isolate number | Year of recovery | emm type | MIC (µg/mL) | Phenotype | Macrolide resistance
genes |
||
|---|---|---|---|---|---|---|---|
| ermA | ermB | mefA/E | |||||
| 186 | 2008 | 68.1 | > 256 | cMLSB | - | + | - |
| 274 | 2008 | 58 | > 256 | iMLSB | + | - | - |
| 302 | 2008 | 58 | > 256 | iMLSB | + | - | - |
| 402 | 2009 | 1 | > 256 | cMLSB | - | + | - |
| 418 | 2009 | 58.14 | 8 | iMLSB | + | - | - |
| 425a | 2009 | 3.3 | 16 | cMLSB | - | + | - |
| 536 | 2010 | 22 | > 256 | cMLSB | - | + | - |
| 637A | 2011 | 1 | > 256 | cMLSB | + | + | - |
| 638 | 2011 | 76.7 | > 256 | cMLSB | + | + | - |
| 710 | 2011 | 28 | > 256 | cMLSB | - | + | - |
| 749 | 2011 | 73 | > 256 | cMLSB | + | + | - |
| 750 | 2011 | 6 | > 256 | cMLSB | + | + | - |
| 780 | 2012 | 11 | > 256 | cMLSB | + | + | - |
| 798 | 2012 | 11 | > 256 | iMLSB | + | + | - |
a
: this isolate was intermediate by disk diffusion; cMLSB: constitutive MLSB phenotype; iMLSB: inducible MLSB phenotype; MIC: minimal inhibitory concentration (susceptible < 0.25 µg/mL, intermediate 0.5 µg/mL, resistant > 1 µg/mL); +: presence of the gene; -: absence of the gene.