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Loss of granulocyte-macrophage colony stimulating factor signalling in non-haematopoietic cells leads to intestinal barrier dysfunction. (A) Ileal paracellular permeability was determined with everted gut sac in wild type (WT), WTBM, GMKO, WTBM→GMRKO and WTBM→GMKO mice (n=10). (B) Ileal epithelial electric resistance (TEER) was determined by clamping the voltage across the epithelium layer mounted in Ussing chambers (n=5). Results are expressed as mean±SEM.
