. Author manuscript; available in PMC: 2015 Jan 16.

Published in final edited form as: J Clin Exp Cardiolog. 2014 Nov 5;5:1000344. doi: 10.4172/2155-9880.1000344

TABLE 3a.

Association of CRP & IL-6 with NAFLD defined by dichotomous liver-to-spleen ratio and liver attenuation < 40HU.

Biomarker	Unadjusted Odds Ratio (95% CI)	Adjusted^* Odds Ratio (95% CI)
LSR < 1
CRP (per doubling)	1.28 (1.22, 1.35)	1.15 (1.08, 1.23)
CRP ≥ 2.00	1.96 (1.65, 2.32)	1.41 (1.16, 1.73)
IL-6 (per doubling)	1.42 (1.30, 1.55)	1.18 (1.05, 1.31)
Liver attenuation < 40HU
CRP (per doubling)	1.44 (1.33, 1.57)	1.31 (1.18, 1.45)
CRP ≥ 2.00	3.11 (2.32, 4.18)	2.27 (1.62, 3.16)
IL-6 (per doubling)	1.60 (1.40, 1.83)	1.33 (1.13, 1.58)

adjusted for age, gender, race, education, BMI, smoking, hypertension, diabetes, LDL cholesterol, HDL cholesterol, lipid lowering medications, triglycerides, waist circumference and glucose.

(Abbreviations: CRP: C reactive protein, IL-6: Interleukin 6, NAFLD: Non alcoholic fatty liver disease, HU: Hounsfield units)