Table 2.
Multivariate logistic regression analysis for cerebro-cardiovascular events
| No. of patients with CVD/total (17/84) | OR | 95% CI | P-value | |
|---|---|---|---|---|
| Age (years) | ||||
| <60 | 4/29 | 1 (Reference) | 0.256–6.871 | 0.737 |
| ≥60 | 13/55 | 1.325 | ||
| Sex | ||||
| Male | 8/48 | 1 (Reference) | 0.672–9.547 | 0.170 |
| Female | 9/36 | 2.533 | ||
| BMI | ||||
| <25 | 7/36 | 1 (Reference) | 0.113–2.123 | 0.340 |
| ≥25 | 10/48 | 0.490 | ||
| Hypertension | ||||
| No | 16/68 | 1 (Reference) | 0.098–3.185 | 0.511 |
| Yes | 1/16 | 0.558 | ||
| HbA1c | ||||
| <7.0 | 1/11 | 1 (Reference) | 0.090–7.639 | 0.868 |
| ≥7.0 | 16/73 | 1.829 | ||
| Dyslipidemia | ||||
| No | 7/42 | 1 (Reference) | 0.219–3.698 | 0.845 |
| Yes | 10/42 | 0.901 | ||
| EPA/AA ratio | ||||
| <0.5 | 12/59 | 1 (Reference) | 0.199–4.530 | 0.948 |
| ≥0.5 | 5/25 | 0.949 | ||
| GSM | ||||
| ≥32 | 5/52 | 1 (Reference) | 1.511–39.540 | 0.014 |
| <32 | 12/32 | 7.730 | ||
| PA (V) | ||||
| <20,000 | 10/52 | 1 (Reference) | 0.159–2.986 | 0.619 |
| ≥20,000 | 7/32 | 0.690 | ||
| Mean IMT (mm) | ||||
| <1.0 | 13/70 | 1 (Reference) | 0.235–6.538 | 0.801 |
| ≥1.0 | 4/14 | 1.239 | ||
| PS (mm) | ||||
| <5.0 | 3/42 | 1 (Reference) | 1.026–20.629 | 0.046 |
| ≥5.0 | 14/42 | 4.601 | ||
AA, arachidonic acid; CI, confidence interval; CVD, cerebro-cardiovascular disease; EPA, eicosapentaenoic acid; GSM, gray-scale median; IMT, intima-media thickness; OR, odds ratio; PA, platelet aggregation; PS, plaque score.
Dyslipidemia is defined as low-density lipoprotein cholesterol ≥140 mg/dL or high-density lipoprotein cholesterol <40 mg/dL or triglycerides ≥200 mg/dL.