Table 3. Study population and published results for included trials.
Protocol | N | M/F (%) | PS 0/1/2 (%) |
PFS | OS |
---|---|---|---|---|---|
ECOG-1298 | 32 | 50 / 50 | 12 / 72 / 16 | 2.1 Median PFS |
4.7 mos Median OS |
ECOG-2297 Arm 1 | 162 | 54 / 46 | 35 / 52 / 14 | 2.2 mos. Median PFS |
5.4 mos. Median OS |
ECOG-2297 Arm 2 | 160 | 52 / 48 | 23 / 64 / 14 | 3.4 mos Median PFS |
6.7 mos Median OS |
ECOG-3296 | 36 | 69 / 31 | 28 / 53 / 19 | 2.4 mos. Median TTF* |
4.3 mos Median OS |
NCCTG-0043 | 48 | 37 / 63 | 34 /58 / 8 | 3.8 mos. Median PFS |
6.7 mos. Median OS |
NCCTG-014C Arm B | 36 | 53 / 47 | 35 / 58 / 7 | 2.4 mos. | 4. 8 mos. |
NCCTG-034A | 82 | 70 / 27& | 40 / 54 /6& | 5.7 mos | 8.1 mos. |
NCCTG-984351 | 46 | 56 / 44 | 35/41 / 20 | 4.5 mos. | 6.2 mos. |
SWOG-0205 Arm 1 | 371 | 54 / 46 | 87 / 13# | 3.0 mos. | 5.9 mos. |
SWOG-0205 Arm 2 | 372 | 51 / 49 | 87 / 13# | 3.4 mos. | 6.3 mos. |
Time to treatment failure
PS 0-1 / 2
Percentages generated from data, not published report