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. Author manuscript; available in PMC: 2015 Aug 15.
Published in final edited form as: Clin Cancer Res. 2014 Jun 9;20(16):4176–4185. doi: 10.1158/1078-0432.CCR-13-2024

Table 3. Study population and published results for included trials.

Protocol N M/F (%) PS 0/1/2
(%)
PFS OS
ECOG-1298 32 50 / 50 12 / 72 / 16 2.1 Median
PFS
4.7 mos
Median OS
ECOG-2297 Arm 1 162 54 / 46 35 / 52 / 14 2.2 mos.
Median PFS
5.4 mos.
Median OS
ECOG-2297 Arm 2 160 52 / 48 23 / 64 / 14 3.4 mos
Median PFS
6.7 mos
Median OS
ECOG-3296 36 69 / 31 28 / 53 / 19 2.4 mos.
Median TTF*
4.3 mos
Median OS
NCCTG-0043 48 37 / 63 34 /58 / 8 3.8 mos.
Median PFS
6.7 mos.
Median OS
NCCTG-014C Arm B 36 53 / 47 35 / 58 / 7 2.4 mos. 4. 8 mos.
NCCTG-034A 82 70 / 27& 40 / 54 /6& 5.7 mos 8.1 mos.
NCCTG-984351 46 56 / 44 35/41 / 20 4.5 mos. 6.2 mos.
SWOG-0205 Arm 1 371 54 / 46 87 / 13# 3.0 mos. 5.9 mos.
SWOG-0205 Arm 2 372 51 / 49 87 / 13# 3.4 mos. 6.3 mos.
*

Time to treatment failure

#

PS 0-1 / 2

&

Percentages generated from data, not published report