Skip to main content
Antimicrobial Agents and Chemotherapy logoLink to Antimicrobial Agents and Chemotherapy
. 1976 Jun;9(6):1066–1069. doi: 10.1128/aac.9.6.1066

Comparison of In Vitro Antimicrobial Activity of Cefamandole and Cefazolin with Cephalothin Against over 8,000 Clinical Bacterial Isolates

Ronald N Jones *, Peter C Fuchs
PMCID: PMC429673  PMID: 938021

Abstract

Antimicrobial susceptibility to cefamandole versus cephalothin and cefazolin versus cephalothin was compared by the broth microdilution method against 3,000 and 5,895 clinical bacterial isolates, respectively. Cefamandole and, to a lesser degree, cefazolin showed greater activity than cephalothin against Enterobacteriaceae, but the three drugs were comparable against gram-positive cocci.

Full text

PDF
1069

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Motley M., Shadomy S. In vitro studies with cefazolin. Antimicrob Agents Chemother. 1974 Dec;6(6):856–861. doi: 10.1128/aac.6.6.856. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Neu H. C. Cefamandole, a cephalosporin antibiotic with an unusually wide spectrum of activity. Antimicrob Agents Chemother. 1974 Aug;6(2):177–182. doi: 10.1128/aac.6.2.177. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Phair J. P., Carleton J., Tan J. S. Comparison of cefazolin, a new cephalosporin antibiotic, with cephalothin. Antimicrob Agents Chemother. 1972 Oct;2(4):329–330. doi: 10.1128/aac.2.4.329. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Reller L. B., Karney W. W., Beaty H. N., Holmes K. K., Turck M. Evaluation of cefazolin, a new cephalosporin antibiotic. Antimicrob Agents Chemother. 1973 Apr;3(4):488–497. doi: 10.1128/aac.3.4.488. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Ries K., Levison M. E., Kaye D. Clinical and in vitro evaluation of cefazolin, a new cephalosporin antibiotic. Antimicrob Agents Chemother. 1973 Feb;3(2):168–174. doi: 10.1128/aac.3.2.168. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Sabath L. D., Wilcox C., Garner C., Finland M. In vitro activity of cefazolin against recent clinical bacterial isolates. J Infect Dis. 1973 Oct;128(Suppl):S320–S326. doi: 10.1093/infdis/128.supplement_2.s320. [DOI] [PubMed] [Google Scholar]
  7. Wick W. E., Preston D. A. Biological properties of three 3-heterocyclic-thiomethyl cephalosporin antibiotics. Antimicrob Agents Chemother. 1972 Mar;1(3):221–234. doi: 10.1128/aac.1.3.221. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Antimicrobial Agents and Chemotherapy are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES