Table 1.
Study | Sample | Demo-graphics | Predictors | Outcomes | Key findings |
---|---|---|---|---|---|
Valcour et al, 2005, 200652,53 |
203 HIV+ | 82% men 20–76 yr |
DM self-report or glucose >125 |
Learning, memory, SIP, executive, motor speed, attention |
DM assoc with HAD (adjusted for other vascular risk factors) |
Becker et al, 200968 | 428 HIV+ 207 HIV− |
100% men 40–65 yr |
Coronary artery calcium, cIMT, lipids, DM, GFR |
Learning, memory, executive, psychomotor speed |
Worse cIMT & GFR assoc → ↓ PM speed |
Wright et al, 201069 | 292 HIV+ | 58% men 30–50 years |
Prior CVD, HTN, ↑ cholesterol | psychomotor speed, executive, SIP |
CVD, HTN, cholesterol → ↓ cognition |
Foley et al, 201070 | 98 HIV+ | 81% men 30–65 years 70% AA |
Self-report DM, HTN, Ml, CHF | Learning, memory, executive, motor, attention, working memory |
CV risk→ ↓ processing speed |
Fabbiani et al, 201271 | 245 HIV+ | 76% men 30–60 years 94% cART |
cIMT, vascular comorbidities (obesity, lipids) |
Learning, memory, executive, psychomotor speed |
DM + cIMT → ↓ cognition |
McCutchan et al, 201254 | 130 HIV+ | 85% men | BMI.WC, DM, HTN, lipids | Learning, memory, executive, motor, attention, SIP |
↑ WC → ↓ cognition |
Abbreviations: AA, African American; cART, combination antiretroviral therapy; CHF, congestive heart failure; cIMT, carotid intima-media thickness; CV, cardiovascular; DM, diabetes mellitus; GRF, glomerular filtration rate; HIV, human immunodeficiency virus; HTN, hypertension; SIP, speeded information processing; WC, waist circumference.