Table 3.

Fecal Incontinence Consistency and Amount per Day by Group in Mixed Model Analysis

	Placeboa n=49b/47c	CMC n=53/47	GA n=50/49	Psyllium n=54/46	Overall Difference from Placebo Baseline	Additional Difference Specific to Fiber Group		p-value
	β(seβ)d	β(seβ)e	β(seβ)e	β(seβ)e	β(seβ)e		β(seβ)f
		FI Consistency
Baseline	2.0 (0.15)	0.12 (0.22)	0.008 (0.22)	0.25 (0.22)
Supplement Period b	2.0 (0.15)	0.15 (0.20)	0.001 (0.20)	0.21 (0.20)	−0.05 (0.14)	CMC	0.13 (0.21)	.42
						GA	−0.06 (0.21)	.76
						Psyllium	−0.20 (0.24)	.52
Supplement Period c	2.1 (0.09)	0.003 (0.12)	−0.03 (0.12)	−0.08 (0.13)	−0.04 (0.07)	CMC	0.17 (0.09)	.08
						GA	−0.07 (0.10)	.46
						Psyllium	−0.05 (0.11)	.63
		FI Amount
Baseline	1.6 (.07)	0.11 (0.09)	−0.04 (0.09)	0.19 (0.09)
Supplement Period b	1.6 (.07)	0.21 (0.12)	−0.03 (0.11)	0.20 (0.12)	−0.04 (0.06)	CMC	−0.09 (0.08)	.28
						GA	−0.08 (0.09)	.43
						Psyllium	−0.02 (0.10)	.99
Supplement Period c	1.6 (.09)	0.18 (0.11)	−0.04 (0.11)	0.20 (0.12)	−0.04 (0.06)	CMC	−0.10 (0.09)	.25
						GA	−0.07 (0.09)	.40
						Psyllium	−0.02 (0.10)	.87

Note. CMC = carboxymethylcellulose. GA = gum Arabic. FI = fecal incontinence. The average FI consistency for the placebo and gum arabic groups was soft but formed in both the baseline and supplement periods; for the CMC group, FI consistency was loose and unformed in both periods, and for the psyllium group, it was loose and unformed in the baseline period and soft but formed in the supplement period. There was no statistical or clinical difference in FI amount among groups.

^aPlacebo group was reference group.

^bintent-to-treat analysis.

^cper-protocol analysis.

^dfor intercept representing the average FI frequency/day of placebo group in the baseline period

^efor difference from placebo in baseline period

^ffor additional difference specific to fiber group in supplement period