Table 2. Genotype and allelic frequencies of rs9923231, rs7294, rs1057910, rs2108622, rs699664 polymorphisms obtained in our population and in other references of Chinese.
Genotype frequencies | Allelic frequencies | ||||||
---|---|---|---|---|---|---|---|
Gene | Our Data | Reference Data | Our Data | Reference Data | |||
N | % | % | % | % | |||
VKORC1 rs9923231 | |||||||
AA | 185 | 84.00 | 83.7–86.16 | A | 91.80 | 91.57–92.61 | [36][37] |
AG | 34 | 15.50 | 12.90–15.70 | G | 8.20 | 7.39–8.43 | |
GG | 1 | 0.50 | 0.60–0.94 | ||||
VKORC1 rs7294 | |||||||
TT | 1 | 0.50 | 1.00–1.45 | T | 8.00 | 5.31–7.30 | [20][21] |
TC | 33 | 15.00 | 7.73–12.70 | C | 92.00 | 92.70–94.69 | |
CC | 186 | 84.50 | 86.30–90.82 | ||||
CYP2C9 rs1057910 | |||||||
AA | 201 | 91.30 | 90.19–90.68 | A | 95.50 | 95.10–95.16 | [38][39] |
AC | 18 | 8.20 | 8.96–9.81 | C | 4.50 | 4.84–4.90 | |
CC | 1 | 0.50 | 0–0.36 | ||||
CYP4F2 rs2108622 | |||||||
AA | 8 | 3.60 | 5.68–8.89 | A | 21.10 | 20.50–28.31 | [26][27] |
AG | 77 | 35.00 | 29.55–38.84 | G | 78.90 | 71.69–79.50 | |
GG | 135 | 61.40 | 52.27–64.77 | ||||
GGCX rs699664 | |||||||
TT | 29 | 13.20 | 9.48 | T | 35.00 | 31.86 | [29] |
TC | 96 | 43.60 | 44.74 | C | 65.00 | 68.14 | |
CC | 95 | 43.20 | 45.77 |