Table 4. Baseline characteristics of patients with target INR (1.5–2.5).
| Gene | SNP | N | Age (year) | p | Body weight (kg) | p | Gender (Males/Females) | p | |
|---|---|---|---|---|---|---|---|---|---|
| VKORC1 | rs9923231 | AA | 134 | 48.54±10.42 | 0.330 △ | 58.75±8.67 | 0.793 △ | 38/96 | 0.936 ☆ |
| AG+ GG | 24 | 46.25±11.28 | 58.23±8.05 | 7/17 | |||||
| rs7294 | TT+ TC | 23 | 47.70±10.12 | 0.809 △ | 59.31±8.03 | 0.710 △ | 8/15 | 0.469 ☆ | |
| CC | 135 | 48.27±10.66 | 58.55±8.67 | 37/98 | |||||
| CYP2C9 | rs1057910 | AA | 147 | 48.01±10.68 | 0.427 △ | 58.84±8.81 | 0.101 △ | 43/104 | 0.730* |
| AC+ CC | 11 | 50.64±8.65 | 56.45±3.62 | 2/9 | |||||
| CYP4F2 | rs2108622 | AA+ AG | 58 | 48.21±9.45 | 0.988 △ | 57.93±7.61 | 0.433 △ | 15/43 | 0.579 ☆ |
| GG | 100 | 48.18±11.19 | 59.12±9.09 | 30/70 | |||||
| GGCX | rs699664 | TT | 24 | 46.63±10.03 | 0.521 ◆ | 55.52±8.58 | 0.109 ◆ | 7/17 | 0.936 ☆ |
| TC+ CC | 134 | 48.47±10.65 | 59.27±8.448 | 38/96 |
Data of age and body weight represented as mean ± SD, and the continuous variables for rs9923231, rs7294, rs1057910, rs2108622 are normalized, except rs699664.
△: normalized data were analyzed by Independent-Samples T test;
◆: non-normalized data were analyzed by Mann-Whitney U test;
☆: data analyzed by χ2-test;
*: data analyzed by fisher exact test.