Table 7. The relationship between plasma concentration and INR in patients carrying polymorphism variants of rs9923231, rs7294, rs2108622 and rs699664.

		INR
Plasma concentration(ng/ml)	N	<1.5 (n = 27)	[1.5–2.5] (n = 92)	>2.5 (n = 11)
rs9923231 (VKORC1)	130
AA	109	913.66±266.13	1117.29±323.23	1009.54±339.53
AG	20	1528.43±623.17	1675.73±431.09	1328.80±15.84
GG	1	-	2298.50	-
p		0.017	<0.001	0.234
rs7294 (VKORC1)
TT	1	-	2298.50	-
TC	20	1528.43±623.17	1675.73±431.09	1328.80±15.84
CC	109	913.66±266.13	1117.29±323.23	1009.54±339.53
p		0.017	<0.001	0.234
rs2108622 (CYP4F2)
AA	6	1557.13±793.26	1161.07±144.99	-
AG	39	950.26±354.96	1284.63±475.94	1293.07±233.87
GG	85	1008.92±375.03	1169.43±372.61	983.04±331.70
p		0.102	0.458	0.177
rs699664 (GGCX)
TT	36	848.00	1209.76±410.63	992.43±416.99
TC	67	1045.92±401.85	1158.14±352.51	1186.10±245.59
CC	27	1068.46±503.82	1405.36±560.57	945.23±429.05
p		0.898	0.206	0.596