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. 2015 Jan 9;10:447–462. doi: 10.2147/IJN.S72920

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© 2015 Li et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Cell membrane structural damage and cell membrane integrity results; (A) cell membrane structural damage after treatment with 0.2 μg/mL CNE (×39,000 times); (B) cell membrane structural damage after treatment with 0.2 μg/mL CHX (×39,000 times); (C) cell membrane structural damage after treatment with 0.2 μg/mL CNE (×93,000 times); (D) cell membrane structural damage after treatment with 0.2 μg/mL CHX (×93,000 times); (E) leaking DNA concentration of Streptococcus mutans treated CNE; (F) leaking protein concentration of S. mutans treated CNE.

Notes: Cell membrane structural damage was remarked with red and arrowed circle. 700610 means S. mutans control. **P<0.01 represents a significant difference; *P<0.05 represents a difference.

Abbreviations: CNE, chlorhexidine acetate; CHX, chlorhexidine acetate water solution; BNE, blank nanoemulsion.