Figure 4.

Axial plane multiphoton microscopy images obtained from the same 3 animals (A, B, C) and regions of repair and normal cartilage as presented in Figures 2 and 3. In all panels, superficial is toward the top of the image. A significant difference was observed between repair and normal cartilage collagen structure. Note that the resolution of multiphoton microscopy is at the cellular level. Autocorrelation ellipticity repair values: A = 4.51, B = 1.92, C = 3.01. Autocorrelation ellipticity normal values: A = 2.46, B = 2.94, C = 2.74.