Table 1.
Femoral surfacea | Tibial/acetabular surface | Extracellular matrixb | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
No. | Inner | Middle | Outer | Inner | Middle | Outer | Inner | Middle | Outer | Intracellularlyc (% lubricin-positive cells) |
Menisci | ||||||||||
1 | 100 | 100 | 100 | 40 | 100 | 100 | ++ | + | + | 5 ± 9 |
2 | 100 | 100 | 100 | 100 | 100 | 100 | +++ | + | + | 8 ± 2 |
3 | 100 | 100 | 100 | 100 | 100 | 100 | ++++ | ++++ | ++ | 4 ± 3 |
4 | 100 | 100 | 100 | 100 | 100 | 100 | ++++ | ++++ | + | 21 ± 14 |
5 | 90 | 70 | 10 | 70 | 60 | 20 | + | + | + | 10 ± 12 |
6 | 100 | 100 | 100 | 100 | 100 | 100 | ++ | +++ | ++ | 7 ± 5 |
7 | 100 | 100 | 100 | 100 | 100 | 100 | ++++ | ++++ | ++++ | 25 ± 9 |
8 | 100 | 100 | 80 | 80 | 70 | 60 | + | + | + | 1 ± 2 |
9 | 90 | 100 | 80 | 100 | 100 | 100 | ++ | + | + | 7 ± 7 |
10 | 100 | 100 | 100 | 100 | 100 | 100 | + | + | +++ | 19 ± 18 |
11 | 100 | 100 | 100 | 100 | 100 | 90 | +++ | +++ | +++ | 18 ± 10 |
12 | 100 | 100 | 100 | 100 | 100 | 100 | + | + | + | 1 ± 2 |
13 | 20 | 30 | 60 | 80 | 90 | 50 | + | + | + | 4 ± 9 |
14 | 80 | 80 | 20 | 60 | 20 | 10 | + | + | + | 4 ± 9 |
15 | 100 | 100 | 100 | 100 | 20 | 80 | ++++ | ++++ | ++ | 16 ± 10 |
16 | 100 | 90 | 100 | 40 | 100 | 100 | +++ | ++++ | +++ | 15 ± 17 |
17 | 100 | 100 | 100 | 100 | 100 | 100 | ++ | ++ | ++ | 17 ± 16 |
18 | 100 | 100 | 100 | 100 | 100 | 100 | + | ++ | + | 9 ±19 |
Labra | ||||||||||
1 | 100 | 100 | 100 | 10 | 5 | 0 | + | + | ++ | 15 ± 18 |
2 | 100 | 100 | 100 | 100 | 100 | 100 | ++++ | + | + | 10 ± 10 |
3 | 100 | 100 | 100 | 20 | 70 | 90 | + | + | + | 2 ± 4 |
4 | 100 | 100 | 100 | 50 | 10 | 0 | ++++ | ++++ | ++++ | 35 ± 28 |
5 | 80 | 40 | 0 | 5 | 0 | 0 | + | ++ | ++ | 11 ± 8 |
6 | 100 | 100 | 100 | 10 | 10 | 0 | ++++ | +++ | ++ | 27 ± 21 |
The linear percentages of the inner, middle, and outer thirds of the femoral and tibial facing surfaces for the menisci and of the femoral and acetabular facing surfaces for the labra were determined.
The degree of lubricin staining of the extracellular matrix was graded from 0 to ++++ as described in the text.
The percentage of cells containing lubricin (i.e., intracellular lubricin) was determined for each sample; mean ± standard deviation for the fields of view evaluated for each sample.