Fig. 2.

Differential effects of PARP inhibitors on PARP inhibition, DNA damage, and apoptosis in TNBC cells. Effects of AG-014699, AZD-2281, ABT-888, or BSI-201 on the levels of PAR, γ-H2AX, and PARP cleavage in MDA-MB-468, MDA-MB-231, and Cal-51 cells. Cells were treated with the indicated concentrations of PARP inhibitors in the presence of 5 % FBS-supplemented DMEM medium for 72 h