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. Author manuscript; available in PMC: 2015 Jan 16.
Published in final edited form as: Breast Cancer Res Treat. 2012 Jun 8;134(2):649–659. doi: 10.1007/s10549-012-2106-5

Fig. 4.

Fig. 4

AG-014699- and AZD-2281-mediated activation of Akt and ERK might be attributable to downregulation of PHLPP expression in MDA-MB-468 cells, a Dose-dependent effects of AG-014699 and AZD-2281 versus ABT-888 on PHLPP expression after 72 h of treatment, b Effect of LY-294002 (10 µM) on AG-014699- and AZD-2281-mediated phosphorylation of Ser473-Akt and ERKs