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. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: Apoptosis. 2015 Feb;20(2):157–173. doi: 10.1007/s10495-014-1065-1

Figure 5.

Figure 5

The three types of ASC PYD interactions (type I, type II, and type III) [8, 59, 78, 107]. Negative charge is marked in red, positive charge is marked in blue, and neutral residues are marked in pink. The ASC-PYD polymer is comprised of three-start helical strands with C3 symmetry, resulting from type 1 interaction in each of the strands and type 2 and type 3 interactions between the strands [59, 78]. A model of the polymer is indicated, showing the interactions in the start helices on the bottom left [59].