Effect of interstimulus interval (ISI) and intensity of subthreshold stimulus on motor evoked potential (MEP). The peak-to-peak amplitudes of MEP were shown. Dotted horizontal line marks the amplitude of MEP with at-threshold single pulse stimulation. The facilitation occurred as a function of ISI and intensity of the subthreshold stimuli. Compared with non-response at 70% resting motor threshold (RMT), some summation effects can been seen at ISI as far apart as 15 ms. However, compared with at-threshold single pulse stimulaiton, summation occured mainly at 1, 1.5 and 3 ms ISIs with the higher subthreshold stimulation, marked with ‘*’ (p<.05). Error bar indicates SE