Hemorrhagic Shock/Resuscitation-induced adhesion molecule expression and leukocyte adhesion are minimized by CO-RM. A, B. HS/R increased the number of adherent and stationary leukocytes compared to sham, control mice (*P<0.05), whereas CO-RM treatment prevented these changes (#P<0.05 compared to shock, control mice). C. CO-RM treatment limited HS/R-induced hepatic ICAM protein levels (red) as determined by immunohistochemistry. D. Furthermore, CO-RM treatment limited HS/R-induced increased levels of soluble ICAM in the serum (*P<0.05 compared to sham, control; #P<0.05 compared to shock, control).